睡眠呼吸暂停和物质使用:一个元分析
Sibylle Mauries1, Benjamin Rolland2, Justine Frija-Masson3
1Département de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat - Claude Bernard, F-75018, Paris, France.
Sleep medicine reviews
|January 21, 2026
概括
这项元分析发现,酒精和阿片类药物使用显著增加了呼吸暂停-呼吸暂停指数 (AHI),表明睡眠暂停情况更差. 在物质使用者中诊断睡眠呼吸暂停对于更好的成治疗结果至关重要.
科学领域:
- 睡眠医学 睡眠医学
- 成精神病学成精神病学
- 公共卫生 公共卫生
背景情况:
- 睡眠呼吸暂停和物质使用障碍 (SUDs) 呈现出双向的负面关系.
- 阻塞性睡眠呼吸暂停综合征 (OSA) 在SUD患者中特别常见.
研究的目的:
- 对常见物质 (酒精,烟草,大麻,阿片类药物,可卡因) 对呼吸暂停-呼吸暂停指数 (AHI) 的影响进行元分析.
- 为了比较物质使用者和非使用者之间的AHI分数.
主要方法:
- 在PubMed. 的系统文献搜索.
- 在元分析中包括28项研究.
- 药物使用者与非使用者之间的平均AHI分数的比较.
主要成果:
- 在酒精使用者中增加的AHI (SMD:0.46,p < 0.001).
- 在阿片类药物使用者中,中央睡眠呼吸暂停的患病率较高 (SMD:0.44,p < 0.001).
- 烟草使用者的AHI增加,尽管在统计学上并不显著. 对大麻和可卡因使用者的数据有限.
结论:
- 睡眠呼吸暂停的诊断和管理对于物质使用患者至关重要.
- 有效的睡眠呼吸暂停治疗可以改善成的预后.
- 在睡眠呼吸暂停和SUD同时发生时,需要量身定制的治疗方法.
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