用人工智能增强的心电图模型用于检测左心室功能障碍:一项比较研究
Philip M Croon1, Machteld J Boonstra2, Cornelis P Allaart3
1Department of Cardiology, Amsterdam Cardiovascular Science, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, USA.
人工智能增强心电图 (AI-ECG) 模型在检测左心室缩功能障碍 (LVSD) 中表现强. 然而,有限的模型可用性阻碍了AI-ECG工具用于LVSD检测的独立验证和比较.
科学领域:
- 心脏病学 心脏病学
- 人工智能的人工智能
- 医疗成像医学成像
背景情况:
- 几种人工智能增强型心电图 (AI-ECG) 模型显示出检测左心室缩功能障碍 (LVSD) 的前景.
- 缺乏在单一群体内进行独立的对比和绩效评估.
- 现有的模型往往由于有限的队列描述和缺乏外部验证而存在高偏差风险.
研究的目的:
- 独立比较已公布的AI-ECG模型对LVSD检测的性能.
- 评估心脏病学中AI-ECG模型的透明度和可重复性.
- 在标准化外部队列中评估AI-ECG模型的性能.
主要方法:
- 对用于LVSD预测的AI-ECG模型进行系统审查.
- 在具有良好表型的心脏磁共振成像注册表中共享AI-ECG模型的外部验证.
- 在整体患者队列和较低复杂度子组中的绩效评估.
主要成果:
- 从35项研究中确定了51个AI-ECG模型,其中许多报告高性能 (AUROC>0.80).
- 独立验证显示受体操作特征曲线 (AUROC) 下的面积在所有患者中从0.83到0.93不等,在较低复杂性的子集中为0.87到0.96.
- 模型的性能在各个子组中保持一致,在ECG中观察到较小的下降,具有广泛的QRS复合体或心房动.
结论:
- AI-ECG模型在LVSD检测方面表现出强的性能,即使在不同人群上进行训练.
- 这项研究是首次对LVSD的AI-ECG模型进行独立验证和对比.
- AI-ECG模型的有限可用性阻碍了全面的独立验证和临床采用.
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