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Updated: Jan 23, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

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通过向XPF/ERCC1复合体,FB23-2和西斯普拉丁协同抑制头部和部状细胞癌

Yaoqi Jiang1,2, Hongshi Cai1,2, Yue Zhu1,2

  • 1Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou, China.

Cancer science
|January 21, 2026
PubMed
概括

FTO抑制剂FB23-2通过抑制DNA修复,增强了西斯在头部和部状细胞癌 (HNSCC) 的疗效. 这种组合疗法抑制瘤生长,并为HNSCC治疗提供了一个有前途的策略.

关键词:
在FB23-2中,FB23-2是最重要的.在 FTO FTO FTO.在XPF/ERCC1中使用.西斯普拉丁 (cisplatin) 是一种制剂.头部和部状细胞癌瘤有协同效应的效应.

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