维特克斯negundo叶子提取物的化学表征和体外生物活性
1Department of Biotechnology and Microbiology, Karnatak University, Dharwad, Karnataka, India.
Biomedical chromatography : BMC
|January 21, 2026
概括
维特克斯negundo叶的提取物显示出显著的抗菌和抗氧化特性. 乙和甲醇提取物是最有效的,支持传统用途和潜在的制药应用.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 医学植物学 医学植物学
背景情况:
- 维泰克斯negundo L. 传统上用于炎症,微生物和氧化应激障碍.
- 它的叶子含有具有治疗潜力的生物活性化合物.
- 对这些特性进行科学验证对于制药开发至关重要.
研究的目的:
- 为了评估Vitex negundo叶提取物的抗菌和抗氧化活性.
- 用光谱学和染色学来表征提取物中的化学成分.
- 为了将植物化学成分与观察到的生物活动相关联.
主要方法:
- 制备乙,甲醇和水性叶子提取物.
- 通过阿加井扩散对四种细菌菌株进行评估的抗菌活性.
- 使用DPPH激素清除试验评估的抗氧化潜力.
- 使用富里叶变换红外 (FT-IR) 光谱和气体染色体质谱法 (GC-MS) 进行化学分析.
主要成果:
- 乙提取物显示出明显的抗菌活性,对抗Bacillus cereus和Bacillus subtilis.
- 乙和甲醇提取物表现出显著的剂量依赖的抗氧化活性.
- FT-IR证实了生物活性化合物的功能组.
- 在乙和甲醇提取物中,GC-MS分别发现了24个和20个化合物,包括isoambreinolide,catechol和phytol.
结论:
- 维特克斯·内贡多 (Vitex negundo) 叶片是生物活性植物化学物质的丰富来源.
- 提取物具有显著的抗菌和抗氧化活性,验证了传统用途.
- 这些发现支持Vitex negundo在制药应用中的潜力.
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