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Updated: Jan 23, 2026

Assay Development for High Content Quantification of Sod1 Mutant Protein Aggregate Formation in Living Cells
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人类G93A突变SOD1与野生型SOD1纤维的结构比较

Yeongjin Baek1, Hyojeong Lee1, Eun-Su Park1

  • 1Department of Agricultural Biotechnology, and Research Institute of Agriculture and Life Sciences, CALS, Seoul National University, Seoul 08826, the Republic of Korea.

Journal of molecular biology
|January 21, 2026
PubMed
概括

研究人员研究了G93A突变中的铜-超氧化解突变酶 (SOD1),这与家族性肌缩侧面硬化症 (ALS) 有关. 研究结果揭示了突变型SOD1和野生型SOD1的共享线索形成途径,为ALS分子机制提供了新的见解.

关键词:
肌缩侧面硬化症 (ALS) (路易·盖里格病) 是一种疾病.冷电子显微镜的使用方法纤维的纤维状纤维.蛋白质聚合蛋白质的聚合物蛋白质溶解过程中的蛋白质溶解.超氧化物脱酶 (SOD) 的使用

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