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Updated: Jan 23, 2026

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在USP8和Hippo/YAP轴之间的正反调节驱动三重阴性乳腺癌进展

Xin Li1,2, Penghe Yang1,3, Tianshi Wang4

  • 1Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, Henan Province, PR China.

Cell death & disease
|January 21, 2026
PubMed
概括

乌比基特异性酶8 (USP8) 稳定了YAP,促进了三阴性乳腺癌 (TNBC) 的进展. 抑制USP8会阻止TNBC的生长,这表明USP8是这种侵袭性癌症的潜在治疗标.

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