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Updated: Jan 23, 2026

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一种超长时间起作用的二度比克特格拉维尔前药物,由一个短的药物动力学尾巴来定义

Mohammad Ullah Nayan1, Brady Sillman1, Srijanee Das1

  • 1Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA.

Nature communications
|January 21, 2026
PubMed
概括

新型超长效应注射抗逆转录病毒药物显示出对HIV-1治疗的前景. 一种同位体原药纳米悬浮剂 (NMXBIC) 在大鼠中维持了六个月的有效比克特格拉维尔 (BIC) 水平,这表明改善HIV-1治疗的潜力.

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