血管内治疗水脑:一个系统的文献综述
Olga Ciobanu-Caraus1, Philip Heesen2,3, Nicolin Hainc4
1Department of Neuroradiology, Heidelberg University, Heidelberg, Germany. olga.ciobanu-caraus@med.uni-heidelberg.de.
Clinical neuroradiology
|January 21, 2026
概括
血管内脑脊液 (CSF) 的转移提供了一种最小侵入性的替代方法,可以替代传统的脑水症转移方法. 早期的结果显示出有希望的安全性和有效性,但需要长期的数据来确认其临床作用.
科学领域:
- 神经外科 神经外科
- 血管内技术 血管内技术
- 最少侵入性手术是最少侵入性的手术.
背景情况:
- 传统的腹腔外皮切换 (VPS) 对于水头有很高的并发症率.
- 内血管技术的创新提供了最少侵入性脑脊液 (CSF) 的转移.
- 沟通头管理正在发展.
研究的目的:
- 系统地审查内血管治疗传播水脑病的发展情况.
- 检查这些新兴疗法的程序技术,疗效和安全性.
- 评估内血管CSF转移的潜力,作为VPS的替代品.
主要方法:
- 在主要数据库 (PubMed/MEDLINE,Embase,Scopus,clinicaltrials.gov) 进行系统的文献搜索,直到2025年3月.
- 在PROSPERO注册时遵守PRISMA指南.
- 由两个审查员进行独立选和数据提取,并进行描述性结果综合.
主要成果:
- 包括16项研究,重点关注eShunt® (14项研究) 和胆道动脉栓塞 (1项研究).
- eShunt®在1年内改善了异常正常压力脑症患者的Timed Up and Go (35.7%),MoCA (+1.6分) 和膀得分 (-3.6s).
- 对于eShunt®,没有报告与设备相关的严重不良事件.
结论:
- 血管内脑液转移是一种新兴的,最少侵入性的选择,用于传达脑.
- 早期发现表明技术可行性和有利的安全概况.
- 来自正在进行的试验的长期数据对于定义其在临床实践中的作用至关重要.
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