[中国10个地区的结核病发病率的流行病学分析]
1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
|January 21, 2026
概括
结核病 (结核病) 发病率因中国的不同地区而异,风险受到年龄,吸烟和饮酒等生活方式因素以及社会经济地位的影响. 较高的BMI,教育和收入与较低的结核病风险有关.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 生物统计学 生物统计学
背景情况:
- 结核病 (TB) 仍然是一个重大的全球卫生挑战.
- 了解结核病发病率和风险因素对于有效的控制策略至关重要.
- 中国Kadoorie生物库 (CKB) 研究为调查中国的结核病流行病学提供了有价值的队列.
研究的目的:
- 确定中国Kadoorie生物银行 (CKB) 研究中的10个特定地区的结核病 (TB) 发病率.
- 识别和分析影响结核病风险的社会人口结构,生活方式和健康相关因素.
- 检查2009年至2018年期间结核病发病率的时间趋势.
主要方法:
- 将CKB队列数据与中国疾病控制和预防信息系统联系起来,以确定结核病例.
- 使用波松回归模型分析结核病发病率分布,并估计相关因素的风险比率 (RR).
- 使用结点回归来检测和分析结核病发病率的时间趋势.
主要成果:
- 结核病发病率存在显著的地理差异,湖南的发病率最高,江的发病率最低.
- 结核病风险增加与老年,吸烟,饮酒和糖尿病有关.
- 高等教育水平,家庭年收入增加和更高的体重指数 (BMI) 等因素与结核病风险降低有关.
- 与男性相比,女性患结核病的风险较低.
- 结核病发病率在2013年达到峰值,随后下降,最初增加,随后每年百分比变化下降.
结论:
- 在研究的CKB地区,结核病发病率在成年人中特别高.
- 社会人口统计学特征,生活方式选择 (包括吸烟和饮酒) 和BMI是结核病风险的重要决定因素.
- 这些发现强调了针对这些影响因素的有针对性的公共卫生干预措施的必要性,以减轻结核病负担.
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