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Updated: Jan 23, 2026

In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity
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异常的SUMOylation限制了可向的癌症免疫组

Uta M Demel1,2,3, Anna Meurer1,2, Badeel Kh Q Zaghla1

  • 1Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 22, 2026
PubMed
概括

在癌症中异常的SUMOylation通过限制的呈现来限制抗瘤免疫力. 抑制SUMOylation恢复了免疫监测,并提高了癌症免疫治疗的有效性.

关键词:
抗原呈现的呈现方式.癌症免疫疗法免疫疗法免疫皮组 (immunopeptidome) 是一个免疫皮组.美国MHC-I苏摩运动是苏摩运动.

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