相关实验视频

Updated: Jan 23, 2026

Visualizing the Effects of Oxidative Damage on Drosophila Egg Chambers using Live Imaging
09:20

Visualizing the Effects of Oxidative Damage on Drosophila Egg Chambers using Live Imaging

Published on: April 10, 2021

4.1K

通过通过PGC-1α通路向氧化应激和线粒体损伤,PACAP可缓解帕克利塔塞尔诱导的外周神经病变

Ruyue Mo1, Chuanming Wang2, Haibei Hu3

  • 1Department of Clinical Laboratory Medicine, Fifth Affiliated Hospital, Southern Medical University, Guangzhou, China.

CNS neuroscience & therapeutics
|January 22, 2026
PubMed
概括

pituitary adenylate cyclase-activating polypeptide (PACAP) 通过增强线粒体功能和减少氧化应激,有效地治疗帕克利塔塞尔诱导的外周神经病变 (PIPN). 这种治疗方法显示出作为辅助癌症治疗的前景.

关键词:
线粒体损伤可能导致线粒体损伤.氧化应激是一种氧化应激.帕克利塔克塞尔 (paclitaxel) 是一种药物.疼痛 疼痛 疼痛 疼痛下垂体腺酸环酶激活.

更多相关视频

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy14:54

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy

Published on: November 29, 2015

9.0K
Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies11:29

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

27.3K

相关概念视频

Nitric Oxide Signaling Pathway01:28

Nitric Oxide Signaling Pathway

Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure...
6.2K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
9.0K
Oxidation Numbers03:14

Oxidation Numbers

In redox reactions, the transfer of electrons occurs between reacting species. Electron transfer is described by a hypothetical number called the oxidation number (or oxidation state). It represents the effective charge of an atom or element, which is assigned using a set of rules.
42.2K
Export of Mitochondrial and Chloroplast Genes02:19

Export of Mitochondrial and Chloroplast Genes

A eukaryotic cell can have up to three different types of genetic systems: nuclear, mitochondrial, and chloroplast. During evolution, organelles have exported many genes to the nucleus; this transfer is still ongoing in some plant species. Approximately 18% of the Arabidopsis thaliana nuclear genome is thought to be derived from the chloroplast’s cyanobacterial ancestor, and around 75% of the yeast genome derived from the mitochondria’s bacterial ancestor. This export has occurred...
4.1K
C4 Pathway and CAM01:27

C4 Pathway and CAM

Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
48.9K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
15.3K