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Updated: Jan 23, 2026

A "Dual-Addition" Calcium Fluorescence Assay for the High-Throughput Screening of Recombinant G Protein-Coupled Receptors
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Published on: December 2, 2022

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通过使用具有代谢能力的高通量选试验来识别雄激素受体对抗剂

Caitlin Lynch1, Pranav Shah1, Jinghua Zhao1

  • 1Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Rockville, MD 20850, USA.

Current research in toxicology
|January 22, 2026
PubMed
概括

这项研究开发了一种高通量选试验,将新陈代谢纳入,以识别雄激素受体 (AR) 抗剂. 发现了一种新的AR抗剂,4,5-dianilinophthalimide (DAPH),它需要代谢激活才能发挥其强烈的抗作用.

关键词:
雄激素受体的受体 雄激素受体代谢过程中的代谢.量化高通量选 通过量化高通量选

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