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Updated: Jan 23, 2026

The Mesenteric Lymph Duct Cannulated Rat Model: Application to the Assessment of Intestinal Lymphatic Drug Transport
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作为载体介导药物相互作用的内源生物标志物,基氨酸的进展

Pengfei Zhao1, Yin Hu1,2, Xinhua Hu1

  • 1Center of Clinical Pharmacology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Frontiers in pharmacology
|January 22, 2026
PubMed
概括

甲 (CPs) 作为生物标志物,有望预测通过有机阴离子载体聚 (OATP1B) 介导的药物相互作用. 整合CP与建模可以提高药物开发的安全性和效率.

关键词:
这是一个OATP1B的OATP1B.在PBPK模型中,甲酸 (CPs) 是一种甲酸.内生生物标志物内生生物标志物载体介导的药物相互作用 (DDI)

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