从第一次滑落到第二次挫折:老年人反复跌倒后的内损伤风险:一项回顾性队列研究
Asmaa Namoos1, Nicholas Thomson Thomson1, Tarek Zaho1
1The Injury and Violence Prevention Program, Departments of Surgery, Virginia Commonwealth University, Richmond, VA 23284, USA.
概括
老年人经常跌倒会增加内损伤 (ICI) 的风险. 抗高血压药和抗抑郁药进一步提高了这种风险,突出了针对性预防跌倒策略的必要性.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 神经学 神经学
背景情况:
- 老年人的反复跌倒是一个重要的公共卫生问题,经常导致严重的伤害,如内伤害 (ICI).
- ICI可以导致认知能力下降,残疾和过早死亡.
- 某些药物,包括抗高血压药和抗抑郁药,可能会增加跌倒相关伤害的风险.
研究的目的:
- 调查老年人反复跌倒与内损伤 (ICI) 风险之间的关联.
- 确定预测该人口中ICI风险的人口和药物相关因素.
主要方法:
- 一项回顾性队列研究,涉及到2023年VCUHS的3760名65-89岁的成年人.
- 患者被分为初始跌倒 (n=2710) 和复发性跌倒 (n=1050) 队列.
- 考克斯回归模型分析了人口统计学变量,药物使用和ICI结果.
主要成果:
- 经常性跌倒与10.4%的ICI风险增加有关 (HR=1.104,p=0.0493).
- 男性性别 (HR=1.369,p=0.0186) 和晚年 (HR=1.021,p=0.0347) 增加了ICI风险.
- 使用抗高血压药几乎使ICI风险增加了一倍 (HR=1.958,p=0.0002),使用抗抑郁药增加了47.1%的风险 (HR=1.471,p=0.0093).
结论:
- 经常性跌倒会增加老年人,特别是男性和老年人的ICI风险.
- 抗高血压和抗抑郁药的使用是增加ICI风险的显著预测因素.
- 识别高风险患者和量身定制药物管理对于减少跌倒相关伤害严重程度至关重要.
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