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Updated: Jan 23, 2026

Synthesis and Evaluation of a Ruthenium-based Mitochondrial Calcium Uptake Inhibitor
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作为双COX-2/ACE2抑制剂的罗胺衍生物:设计,合成和抗炎评估

Hala Afifi1,2, Samar S Fatahala3, Rania H Abd El-Hameed3

  • 1Research Directorate, City University Ajman, Ajman, United Arab Emirates.

Frontiers in molecular biosciences
|January 22, 2026
PubMed
概括

新的pyrrolopyrimidine衍生物作为双重向的抗炎药物. 化合物5a和5b有效抑制循环氧化酶-1/2 (COX-1/COX-2) 和血管素转化酶2 (ACE2),提供潜在的炎症和病毒性疾病.

关键词:
抑制了ACE2的发生.抑制了COX-2的发生.这就是SARS-CoV-2病毒.细胞因子 细胞因子分子对接/模拟对接皮罗罗皮里米丁酸盐是什么

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