患有类风湿性关节炎的患者中脱脂症的患病率和模式:回顾性队列研究
Muna M Aldhuhoori1, Ibtehal Makki1, Maryam Alnuaimi1
1Family Medicine, Graduate Medical Education, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, ARE.
Cureus
|January 22, 2026
概括
脱脂症在迪拜的类风湿性关节炎 (RA) 患者中很常见,在诊断前影响了75%的患者. 监测脂质概况对于降低RA患者心血管疾病 (CVD) 风险至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
背景情况:
- 失脂症是类风湿性关节炎 (RA) 的一个显著的并发症,增加了心血管疾病 (CVD) 的风险.
- 在RA群体中脱脂症的患病率和模式需要进一步研究以进行有针对性的干预.
- 了解RA中的失脂症是减轻相关心血管风险的关键.
研究的目的:
- 为了确定在迪拜的RA患者中脱脂症的患病率和模式.
- 分析RA诊断前,期间和之后的脂质状况变化.
- 探索与 RA 患者心血管风险相关的人口和实验室因素.
主要方法:
- 使用迪拜医院电子病历数据进行的回顾性队列研究 (2019年1月 - 2020年12月).
- 包括104名成人RA患者 (21-65岁) 在综合的人口和实验室数据中.
- 与RA诊断相比,对不同疾病阶段的脂质特征进行分析.
主要成果:
- 在诊断前在RA患者中观察到高患脂质不良症的高患病率 (75%),较高的LDL最常见.
- 在RA诊断时,73.1%的患者患有脂质不良症,主要是HDL低;诊断后,69.2%的患者患有脂质不良症,主要是高的LDL.
- 在所有疾病阶段都存在显著的脂质异常,没有发现人口统计学关联.
结论:
- 这项研究证实,在迪拜的RA患者队列中,脱脂症的患病率很高.
- 强调需要定期监测RA患者的脂质状况.
- 强调有效的失脂症管理的重要性,以减少心血管疾病风险并改善患者的治疗结果.
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