基于益生菌干预的化疗期间,在晚期消化系统恶性瘤患者的综合护理:关于改善胃肠功能和预防并发症的随机对照研究
Feng Huang1, Qi Zhuo1, Lijuan Zhang1
1Department of Day Treatment Room, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, National Health Commission Key Laboratory of Cancer Metabolism, Fuzhou, Fujian, China.
Frontiers in cellular and infection microbiology
|January 22, 2026
概括
综合护理方案与益生菌相结合,在接受化疗的晚期消化系统癌症患者中显著改善了胃肠功能,营养状况和生活质量. 这种干预减少了并发症,提高了患者的幸福感.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 护理 护理 护理 护理
背景情况:
- 晚期消化系统恶性瘤的化疗往往导致胃肠道功能障碍和并发症.
- 改善患者的生活质量和减少副作用是癌症护理的关键方面.
研究的目的:
- 研究综合护理方案加益生菌干预对晚期消化系统恶性瘤化疗患者胃肠功能,并发症和生活质量的影响.
- 为优化化疗护理提供基于证据的支持.
主要方法:
- 一项随机对照试验,涉及300名接受化疗的晚期消化系统恶性瘤患者.
- 观察组接受了综合护理以及益生菌,而对照组接受了传统护理.
- 胃肠道功能,营养状况,生活质量和并发症在8周内使用经过验证的得分和指标进行评估.
主要成果:
- 与对照组相比,观察组在2,4周和8周 (P<0.05) 显示胃肠功能显著改善 (得分较低).
- 在观察小组中观察到改善的营养状况 (血清白蛋白,白蛋白前,BMI) 和更高的生活质量得分 (P<0.01).
- 干预组的非传染性并发症减少,护理满意度增加 (P<0.05).
结论:
- 综合护理方案与益生菌干预相结合,为接受化疗的晚期消化系统恶性瘤患者提供了显著的临床益处.
- 这种综合方法有效地改善了胃肠功能,营养状况和生活质量,同时减少了并发症.
- 这些发现支持了这种联合干预在瘤护理实践中的治疗价值.
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