使用综合食品化合物数据库和食品摄入数据计算化合物摄入水平
Marie Y Meima1,2, Joost Westerhout1, Sabina Bijlsma1
1The Netherlands Organization for Applied Scientific Research, Utrecht, The Netherlands.
Current developments in nutrition
|January 22, 2026
概括
这项研究估计了炎症性肠病 (IBD) 患者的饮食化合物摄入量. 维生素,矿物质,脂肪酸和多的计算摄入水平被发现是合理的,为未来的食品健康研究奠定了基础.
科学领域:
- 营养科学 营养科学
- 分子营养分子营养学
- 饮食流行病学 饮食流行病学
背景情况:
- 连接饮食与疾病的机制在很大程度上是未知的.
- 在分子化合物水平上分析食物提供了潜在的新见解.
- 之前的工作整合了三个食品化合物数据库.
研究的目的:
- 将综合食品化合物数据库与食物摄入数据结合起来.
- 为了估计患者的化合物摄入水平.
- 评估这些估计摄入水平的可信性.
主要方法:
- 使用食品频率问卷 (FFQ) 来自135名成人炎症性肠病 (IBD) 患者的数据.
- 将FFQ数据转化为770种化合物的摄入值.
- 通过比较计算的摄入百分位数与人口数据和文献基准来评估可信性.
主要成果:
- 计算的维生素和矿物质摄入量p50值在荷兰人口数据的第5至90百分位之间.
- 脂肪酸和多的摄入范围与文献值重叠,尽管有一些偏差.
- 偏差可能归因于区域饮食差异和缺乏标准化的基准.
结论:
- 该研究使用荷兰队列数据为许多饮食化合物提供了可信的摄入量估计.
- 这项研究为进一步的食品健康调查奠定了基础.
- 该方法使得在疾病研究中能够在分子水平上分析饮食.
相关概念视频
Regulation of Food Intake
2.3K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
2.3K
Regulation of Water Intake
2.6K
Osmolality refers to the number of solute particles per kilogram of solvent in a solution. Plasma osmolality specifically indicates the total number of solute particles per kilogram of water in blood plasma. This value reflects the body's hydration status and is tightly regulated through mechanisms controlling water intake and output. While water consumption is a conscious decision, the body has intrinsic regulatory systems to maintain fluid balance. Dehydration, a state of water deficit...
2.6K
Molecules and Compounds
68.3K
Atoms and Molecules
68.3K
Organic Compounds
56.8K
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
56.8K
Elements and Compounds
103.3K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond.
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
103.3K
Solubility of Ionic Compounds
68.1K
Solubility is the measure of the maximum amount of solute that can be dissolved in a given quantity of solvent at a given temperature and pressure. Solubility is usually measured in molarity (M) or moles per liter (mol/L). A compound is termed soluble if it dissolves in water.
68.1K


