相关实验视频
Updated: Jan 23, 2026

11:19
Oral Biofilm Formation on Different Materials for Dental Implants
Published on: June 24, 2018
12.1K
瑞典老龄化人口中口腔微生物群的牙疾病负担很高:基于观察登记的观察性研究
Anders Esberg1, Simon Haworth1,2, Ingegerd Johansson1
1Department of Odontology, Umeå University, Umeå, Sweden.
Frontiers in oral health
|January 22, 2026
概括
瑞典老年人 (54-84岁) 的口腔微生物群是多样而稳定的. 与疾病相关的物种与活跃的口腔疾病有关,而不是终身牙状况,突出了老化口腔健康研究的重要方法.
科学领域:
- 微生物学 微生物学
- 老年学是指老年学的学科.
- 牙科公共卫生 牙科公共卫生
背景情况:
- 老龄化人口面临着相当大的牙和全身疾病负担.
- 关于老年人群口腔微生物群的研究有限.
- 了解口腔微生物组的变化对于老年人健康至关重要.
研究的目的:
- 在老年瑞典人 (54-84岁) 中描述口腔微生物群的多样性和组成.
- 评估口腔微生物群和宿主特征之间的关联.
- 评估与潜在牙和牙周状况的联系.
主要方法:
- 16S rRNA基因测序用于唾液微生物群分析.
- 从初级保健记录中获得的牙科数据.
- 部分最小平方回归和两部分回归模型.
主要成果:
- 口腔微生物群在老龄化个体中保持多样性,没有显著的变化.
- 与疾病相关的物种与活跃疾病指标相关.
- 没有发现与终身牙状况指标 (例如,腐烂,填充,缺失表面) 的关联.
结论:
- 在老化口腔微生物组研究中,方法方面的考虑至关重要.
- 为序列读数进行调整,除了相对丰富之外,也很重要.
- 仔细选择口腔疾病指标在老龄化人口中至关重要.
相关概念视频
Observational Studies
10.8K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
10.8K
Conservation of Small Populations
16.7K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
16.7K
What is Population Genetics?
64.5K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.5K
Population Growth
28.0K
Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.
28.0K
What are Populations and Communities?
37.3K
Overview
37.3K
Naturalistic Observations
17.0K
If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
17.0K

