三台自动化尿沉积物分析仪的比较评估,不包括与切断关联的权衡
Jinho Lee1, Heekang Choi1, Hanmil Jang1
1Department of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
iScience
|January 22, 2026
概括
自动化尿液分析仪在性能上有所不同. 流细胞计 (UF-5000) 在检测细菌和粘液方面表现出色,而成像分析仪 (UAS800,Cobas u701) 对其他元素显示出不同的结果.
科学领域:
- 临床化学 临床化学
- 尿分析技术 尿分析技术
背景情况:
- 将自动化尿沉积物分析仪进行比较是具有挑战性的,因为截止点各不相同.
- 接收器操作特征 (ROC) 分析对于性能评估至关重要.
研究的目的:
- 评估和比较UF-5000,UAS800和Cobas u701自动化尿液分析仪的诊断性能.
- 根据分析器操作机制来识别性能差异.
主要方法:
- 总共分析了774个尿样.
- 手动显微镜和微生物培养作为参考标准.
- 接收器操作特征 (ROC) 分析和DeLong的测试用于比较.
主要成果:
- 在检测显著的细菌尿和粘膜线方面,UF-5000 (流细胞计) 性能优于UAS800和Cobas u701 (成像).
- 在晶体检测方面,UF-5000表现较差.
- UAS800和Cobas u701的整体性能相似,但在检测红细胞,精子和显著的细菌尿症方面有显著差异.
结论:
- 分析器的操作机制是影响性能的一个关键因素.
- 即使是具有类似机制的分析仪也可以显示出显著的性能差异.
- ROC分析提供了一种可靠的方法来比较自动化尿液分析平台.
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