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Updated: Jan 23, 2026

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SLC39A8通过调节骨髓瘤中β-catenin/TCF4/GPX4信号来抑制铁亡

Siliang Tang1, Guojun Tang1, Liangyuan Chen1

  • 1Department of Spine Surgery, the Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.

Current molecular medicine
|January 22, 2026
PubMed
概括

溶性载体家族39成员8 (SLC39A8) 通过通过Wnt/β-catenin通路抑制铁亡,促进骨肉瘤 (OS) 的进展. 抑制SLC39A8抑制了瘤生长,并在OS细胞中诱导了铁亡.

关键词:
骨质肉瘤骨质肉瘤是什么在 SLC39A8A8 中.铁性化 (ferroptosis) 是一种迁移. 迁移. 这就是迁移.它们的扩散和扩散.在β-catenin/TCF4信号传输中.

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