左心房附属体形态的性别和种族差异
Ahmed Wahaj1, Madeline E Mauri2, Matthew J Bocchese2
1Rawalpindi Medical University Rawalpindi Pakistan.
Journal of the American Heart Association
|January 22, 2026
概括
患有心房的黑人患者患有更高的花菜左心房尾形态,这是高中风险因素. 这一发现表明,与LAA解剖相关的中风风险存在潜在的种族差异.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 黑人或女性心房动患者的中风发生率更高.
- 特定的左心房附属体 (LAA) 形态与增加中风风险有关.
- 在LAA解剖学中的种族和性别差异以及它们与中风风险的关联在很大程度上尚未被探索.
研究的目的:
- 调查患者种族和性别与LAA形态学的潜在关联.
- 探索LAA的解剖学差异是否有助于黑人和女性AF患者中风风险差异.
主要方法:
- 对211名患者的计算机断层扫描 (CT) 扫描进行了LAA形态分析.
- 使用基于血栓风险的评分系统来对LAA形态进行分类 (翅,风,仙人掌,白菜).
- 统计分析,包括威尔科克森等级和费舍尔精确测试,用于比较种族和性别群体的形态流行率和得分. 后勤回归确定了种族/性别和高风险LAA形态之间的关联.
主要成果:
- 在黑人和非黑人患者之间,或在男性和女性之间,没有观察到预测中风风险得分的显著差异.
- 与最高中风风险相关的"花菜"LAA形态在黑人患者中明显比非黑人患者更为普遍 (调整后OR,4.8;P=0.035).
- 虽然"花菜"形态在女性中更频繁,但这一发现没有达到统计学意义 (P=0.063).
结论:
- "花菜"LAA形态,中风的高风险因素,显示在黑人患者中更高的患病率.
- 观察到的性别之间的LAA形态差异没有达到统计学意义.
- 这些初步发现表明,由于LAA解剖学,中风风险可能存在种族差异,尽管研究的统计能力有限,但需要进一步调查.
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