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其他HPV类型的非HPV类型16-18以外的其他HPV类型的先入侵性病变发生率

Tuğçe Baykara¹, İbrahim Serdar Serin², Mehmet Dolanbay¹

¹Acıbadem Kayseri Hospital, Clinic of Obsterics and Gynecology, Kayseri, Türkiye.

Turkish journal of obstetrics and gynecology

|January 22, 2026

概括

在正常细胞学和高风险人类乳头瘤病毒 (HR-HPV) 阳性患者中,检测到16.9%的前入侵性病变. 即使在正常的细胞学中,对于由于其他HR-HPV类型引起的可疑病变,也建议进行结肠镜检查.

科学领域:

妇科妇科妇科妇科
在瘤学瘤学.
病毒学病毒学

背景情况:

宫癌查依赖于细胞学和人类乳头瘤病毒 (HPV) 测试.
高风险HPV (HR-HPV) 类型16和18是最致癌的,但其他HR-HPV类型也构成风险.
即使有正常的宫细胞检查结果,也可能出现前入侵性病变.

研究的目的:

调查正常细胞学但对HR-HPV类型阳性的16和18以外的患者中侵袭前病变的患病率.
确定与侵袭前宫病变相关的不同HR-HPV类型的比例.

主要方法:

对342名细胞质正常,接受HR-HPV检测的患者的回顾性分析.
检查了活检结果,以确定侵袭前病变和相关的HPV类型.
患者被分为两组:HR-HPV阳性 (不包括16-18型) 和HPV16-18阳性.

主要成果:

在342名细胞质正常的患者中,58名 (16.9%) 患有HR-HPV阳性和侵袭前病变.
在15.7%的病例中发现了高度状内皮病变 (HSIL) 和低度状内皮病变 (LSIL).
状细胞癌和混合表面上皮质癌分别在0.92%和0.3%的病例中被检测出来.

结论:

大约一半的侵袭前病变与HPV类型16或18有关.
除了16型和18型,其他HR-HPV类型也与显著的侵袭前和侵袭性宫病变率有关.
对于可疑的宫病变,即使有正常细胞检查,也建议进行结肠镜检查和活检,以检测潜在的前入侵性疾病.

关键词:

宫癌是发生在宫癌的原因之一.科尔波斯科比 (colposcopy) 是一种对体检的方法.人类乳头瘤病毒人类乳头瘤病毒

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