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Updated: Jan 23, 2026

Delivery of Antibodies into the Murine Brain via Convection-enhanced Delivery
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增强的mRNA传递使用超声波传递为生物直角连接

Emilio Di Ianni1, Jueun Jeon2, Sedra Mohammadi2

  • 1Department of Neurology, Molecular Neurogenetics Unit, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.

Angewandte Chemie (International ed. in English)
|January 22, 2026
PubMed
概括

这项研究引入了一种新的超声导向预准策略,以增强使用脂质纳米粒子 (LNP) 向肝外组织传递信使RNA (mRNA). 这种方法在体内显著改善了向传递和基因表达.

关键词:
生物对等的预先定位.聚焦式超声波 (FUS) 是指聚焦式超声波.核酸输送核酸的交付方式有针对性的药物输送.

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