相关实验视频
Updated: Jan 23, 2026

11:21
Robotic Ablation of Atrial Fibrillation
Published on: May 29, 2015
20.1K
脉冲场与无线电频率废除用于心房动:BEAT PAROX-AF试验
Pierre Jais1,2,3,4, Petr Neuzil5, Daniel Scherr6
1Univ Bordeaux, 351 cours de la Libération, 33522 Talence, France.
European heart journal
|January 22, 2026
概括
脉冲场移除 (PFA) 显示了类似的单一程序成功的射频移除 (RFA) 药物耐药性心房动 (AF). 虽然PFA的安全事件较少,但它在本试验中没有证明优越.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 耐药性心房动 (AF) 是一个重大的临床挑战.
- 导管切除是AF的关键治疗方式.
- 将脉冲场除 (PFA) 等新型除技术与已知方法 (如射频除 (RFA)) 进行比较至关重要.
研究的目的:
- 为了比较PFA与RFA在患有耐药性偏激素性AF的患者中的单一手术疗效和安全性.
- 为了确定PFA是否在单一程序中提供与RFA相比更好的结果.
主要方法:
- 进行了一项欧洲多中心随机对照优越性试验 (BEAT PAROX-AF).
- 符合条件的患有症状,耐药性 Paroxysmal AF 的患者被随机 (1:1) 分给 PFA 或 RFA.
- 主要终点是12个月后单次手术的成功率,定义为缺少心律失常复发,心脏转变,恢复抗心律失常药物或重复切除.
主要成果:
- 12个月后单一程序的成功率为PFA的77.2% (n=145) 和RFA的77.6% (n=143),没有显著差异 (调整后的差异为0.9%;P = .84).
- 与程序相关的严重不良事件在PFA组 (3.4%) 与RFA组 (7.6%) 相比较较低.
- 没有死亡,持续性麻或中风发生;在RFA组中发现了肺静脉狭窄和坦波纳等特定不良事件.
结论:
- 单次注射的PFA在单次手术后实现从心房失常症中解放的效果并不比点对点的RFA更好.
- 在本研究人群中,PFA与较少的安全事件有关.
- 可能需要进一步的研究,以充分阐明与RFA相比,PFA的长期疗效和安全性.
更多相关视频
04:58Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation
Published on: August 25, 2022
2.5K
08:10Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
2.1K
相关概念视频
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
1.7K
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
1.7K
Amyloid Fibrils
11.7K
Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
11.7K
Amyloid Fibrils
6.4K
6.4K
Beats
1.4K
The study of music provides many examples of the superposition of waves and the constructive and destructive interference that occurs. Very few examples of music being performed consist of a single source playing a single frequency for an extended period of time. A single frequency of sound for an extended period might be monotonous to the point of irritation, similar to the unwanted drone of an aircraft engine or a loud fan. Music is pleasant and exciting due to mixing the changing frequencies...
1.4K
Pulse
2.0K
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
The pulse serves as a clinical...
2.0K
Pulse
3.5K
The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
3.5K