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Updated: Jan 23, 2026

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PI3Kδ抑制剂罗吉诺利西布 (IOA-244) 保持T细胞的功能和活动

Elise Solli1,2, Alessio Bevilacqua3, Mathias Wenes4,5

  • 1Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Norway.

Molecular oncology
|January 22, 2026
PubMed
概括

罗吉诺利西布有效地向白血病细胞,像idelalisib一样,但更好地保留T细胞功能. 这种PI3K抑制剂可能为血液癌症治疗提供更安全的替代方案.

关键词:
在CD4+ T辅助细胞中.CD8+ 细胞毒性 细胞毒性这是一种PI3K抑制剂.T细胞的功能功能T细胞的功能慢性淋巴细胞白血病 慢性淋巴细胞白血病监管T细胞的监管性T细胞

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