Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Relative Risk01:12

Relative Risk

2.0K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.0K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.3K
Design Example: Analyzing Capacity Contours for Flood Risk Assessment01:17

Design Example: Analyzing Capacity Contours for Flood Risk Assessment

289
Flood risk assessment involves careful planning and analysis to ensure the safety of communities near water retention structures. Capacity contours are a vital tool in this process, as they illustrate the potential spread of water at specific levels in a given area. In the context of building a bund across a small valley, these contours play a critical role in evaluating the safety of nearby residential areas.In this example, the bund is intended to store stormwater in the valley. The engineers...
289
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

534
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
534
Lifestyle Factors and Health01:20

Lifestyle Factors and Health

431
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
431
Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

632
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
632

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Increased Arrhythmic Risk in Obesity Is Transduced by Adipose Tissue-Derived Extracellular Vesicles.

JACC. Basic to translational science·2026
Same author

Surgical and clinical predictors of successful Hartmann reversal procedure after perforated diverticulitis.

Surgical endoscopy·2026
Same author

Endoscopic recurrence of Crohn's disease following laparoscopic versus robotic ileocolic resection.

Techniques in coloproctology·2026
Same author

Genetically predicted cytotrophoblast gene expression is associated with birth weight and adult body mass index.

Placenta·2026
Same author

Perioperative risk factors for short- and long-term respiratory morbidity in patients with esophageal atresia.

Journal of pediatric surgery·2026
Same author

Response of an Infant With Presumed Multiple Acyl-CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation.

American journal of medical genetics. Part A·2026
Same journal

Breaking the Polytrauma-Brain Barrier: Using Point-of-Care Biomarkers in Severely Injured Trauma Patients.

Journal of the American College of Surgeons·2026
Same journal

Going the Extra Mile: Picking the Right Trauma Center Destination for Critically Injured Patients in a Mature State-Wide Trauma System.

Journal of the American College of Surgeons·2026
Same journal

What Does It Mean for Surgeons to Be Flourishing?

Journal of the American College of Surgeons·2026
Same journal

Tailor-Made Solution to Trimming Venous Thromboembolism Risk.

Journal of the American College of Surgeons·2026
Same journal

NIH Funding in Surgical Artificial Intelligence: Who, What, Where, Why.

Journal of the American College of Surgeons·2026
Same journal

Efficacy and Safety of Rezūm Water Vapor Thermal Ablation in Large and Small Prostates: A Multicenter Comparative Analysis of 2,725 Patients.

Journal of the American College of Surgeons·2026
查看所有相关文章

相关实验视频

Updated: Jan 23, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

87.6K

遗传风险,健康的生活方式,以及皮炎风险分层.

Thomas E Ueland1, John P Shelley1, Jonathan D Mosley2,3

  • 1Vanderbilt University School of Medicine, Nashville, TN.

Journal of the American College of Surgeons
|January 22, 2026
PubMed
概括
此摘要是机器生成的。

遗传倾向和健康生活方式得分都预测了严重的分炎风险. 将这些分数结合起来,可以为个性化干预提供更好的风险预测.

关键词:
多基因风险得分的多基因风险得分.管炎是一种管炎.基因对环境 基因对环境生活方式 生活方式

更多相关视频

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
10:11

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Published on: October 22, 2014

19.6K
Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.6K

相关实验视频

Last Updated: Jan 23, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

87.6K
Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
10:11

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Published on: October 22, 2014

19.6K
Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.6K

科学领域:

  • 胃肠病学 胃肠病学
  • 遗传学 是一个遗传学.
  • 预防医学 预防医学

背景情况:

  • 多基因风险评分 (PRS) 估计了对疾病的遗传易感性.
  • 生活必需品8 (LE8) 评分评估了对健康生活方式的坚持.
  • 这项研究研究了PRS和LE8在严重椎炎风险分层中的联合实用性.

研究的目的:

  • 评估严重管炎的遗传风险和生活方式因素的独立和联合预测能力.
  • 确定多基因风险评分是否补充生活方式信息以改善风险评估.
  • 开发和验证疾病特定的生活方式分数用于膜炎.

主要方法:

  • 一种针对严重椎炎的PRS被开发并在BioVU验证,然后应用于英国生物银行队列.
  • 计算了包括饮食,运动,吸烟,睡眠,体重,胆固醇,血糖和血压在内的生命必需8 (LE8) 评分.
  • 考克斯的比例危险模型和因相互作用而导致的相对过度风险 (RERI) 用于评估风险和相互作用.

主要成果:

  • 在225,592名英国生物库参与者中,2584人在14年内发展出严重的分泌炎.
  • 具有高遗传风险和生活方式风险的个体患重症分泌体炎的风险增加了4.71倍 (p < 0.01).
  • 遗传风险和生活方式风险的综合影响超过了个别风险的总和 (RERI = 0.98).

结论:

  • 多基因风险评分和生活方式评分都独立地与严重的分炎有关.
  • 整合遗传和生活方式数据提供了超出个人评估的附加风险信息.
  • 包括遗传学和生活方式在内的个性化风险概况可能有助于就干预措施的共同决策.