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Updated: Jan 23, 2026

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
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在探索T. 通过查加斯盒查和AVN-944抑制,IMPDH作为一个有前途的目标

Angel Lobo-Rojas1, Letícia Marchese1, Amanda G Eufrasio1

  • 1Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo, Brazil.

Antimicrobial agents and chemotherapy
|January 22, 2026
PubMed
概括

查加斯病的治疗方法有限. 研究人员确定了因诺辛单酸脱酶 (IMPDH) 作为一种可用药物的标,AVN-944显示出对Trypanosoma cruzi的承诺.

关键词:
在AVN-94444中使用.查加斯病是查加斯病的一种疾病.试osoma cruzi 是一种类型的虫.药物重新定位 药物重新定位药物重用是为了改变药物的用途.简单地说,我可以接受它.精氨酸救援途径的纯素救援途径

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