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Updated: Jan 23, 2026

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AAV-DJ介导的MYOC沉默作为一种基因治疗方法,用于肌林相关的玻璃眼

Yue Wan1, Xiangxiang Liu1, Xuejing Yan2

  • 1Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Investigative ophthalmology & visual science
|January 22, 2026
PubMed
概括

使用腺相关病毒血清型DJ (AAV-DJ) 载体进行基因疗法以使MYOC沉默,显示出它对治疗青光眼的前景. 这种方法减少了MYOC相关的玻璃眼的小鼠模型中的病理标志物,并保留了视力.

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