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Updated: Jan 23, 2026

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一种titin误解变体驱动着心房电力改造,并与心房有关

Mahmud Arif Pavel1, Hanna Chen1, Michael Hill1

  • 1Division of Cardiology, Department of Medicine, University of Illinois at Chicago, Chicago, United States.

eLife
|January 22, 2026
PubMed
概括

罕见的丁丁 (TTN) 误解变体 (TTNmvs) 与心房 (AF) 有关. 一种特定的TTN变异破坏了心脏细胞中的离子通道功能和处理,导致AF的发病.

关键词:
这些是HiPSC-aCMs.由HiPSC衍生的心房心肌细胞.人类 人类 人类 人类 人类 人类 人类这就是 iPSC 的意义.诱导干细胞诱导干细胞医学 医学 医学 医学 医学再生医学是一种再生医学.干细胞是干细胞的组成部分.

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