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Updated: Jan 23, 2026

Polyelectrolyte Complex for Heparin Binding Domain Osteogenic Growth Factor Delivery
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作为设计用于siRNA输送的双功能抗体的模块,Staufen dsRNA结合域

Yahui Liu1, Yan Zheng1, Ruolin Xu1

  • 1Department of Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wuhan University, Wuhan, Hubei 430071, China.

Nucleic acids research
|January 22, 2026
PubMed
概括

双功能抗体将小干扰RNA (siRNA) 结合而非结合,使各种细胞类型的基因沉默成为可能. 提高siRNA功效可以提高疗效,但高亲和度结合对于治疗应用至关重要.

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