确定埃斯瓦提尼需要的最低资源,以实现其2030年结束艾滋病毒流行病的目标
Cebisile Ngcamphalala1, Yao-Rui Yeo1, Jasmine I-Shin Su1
1New York University Grossman School of Medicine, Department of Population Health - Division of Comparative Effectiveness and Decision Science.
Journal of acquired immune deficiency syndromes (1999)
|January 22, 2026
概括
埃斯瓦提尼可以通过战略性资金重新分配或额外的800万美元实现其2030年艾滋病毒发病率减少目标. 优先考虑高影响力的干预措施,如艾滋病毒检测和治疗 (HST) 和长效暴露前预防 (LA-PrEP) 是关键.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 卫生经济学 卫生经济学
背景情况:
- 全球艾滋病毒/艾滋病资金正在下降,需要有效的干预策略.
- 埃斯瓦提尼的目标是到2030年实现艾滋病毒发病率的90%降低,与结束艾滋病毒流行病 (EHE) 倡议保持一致.
研究的目的:
- 为埃斯瓦提尼评估最佳的艾滋病毒干预组合,以实现2030年EHE目标.
- 在资源限制范围内,确定成本有效的策略来避免新的艾滋病毒感染.
主要方法:
- 利用埃斯瓦提尼的人口统计和支出数据进行艾滋病毒干预.
- 采用经过验证的艾滋病毒传播模型来模拟2022-2030年间的干预影响 (成本,预防感染,获得QALY).
- 评估了11种干预组合,包括资源重新分配场景.
主要成果:
- 目前的资源分配将推迟埃斯瓦提尼实现EHE目标.
- 额外的800万美元用于扩大艾滋病毒检测和治疗 (HST) 和长效暴露前预防 (LA-PrEP) 对高风险群体,以及加强违规者追踪和风险沟通,可以在2030年前避免3,500个额外的感染.
- 从效率较低的干预措施重新分配到更高效的干预措施也可以帮助实现EHE目标.
结论:
- 埃斯瓦提尼可以通过增加资金或战略性重新分配现有资源来实现其EHE目标.
- 结果为高艾滋病毒负担,资源有限的环境中资源分配提供了实际指导.
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