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Updated: Jan 23, 2026

Electroporation of Functional Bacterial Effectors into Mammalian Cells
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紧的细菌重组复合体驱动了哺乳动物细胞中高效的千基基量级敲门作用

Yining Luo1,2, Qin Jiang1,2, Yuanhao Qu3,4

  • 1Department of Physiology, School of Basic Medical Science, Nanjing Medical University, Nanjing, Jiangsu, 211111, China.

Nucleic acids research
|January 22, 2026
PubMed
概括

研究人员通过利用细菌蛋白来促进大DNA插入的同质导向修复 (HDR) 来增强哺乳动物细胞中的精确基因组编辑. 这一突破提高了基因编辑效率,用于潜在的治疗应用.

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