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瘤形态作为新诊断的膀癌肌肉侵入性的风险因素:分层分析
Ngoc-The Do1, Lam Nguyen Tung1, Dinh Nguyen Cong1
1Urology and Andrology Center, 108 Military Central Hospital, Hanoi, Vietnam.
Asian Pacific journal of cancer prevention : APJCP
|January 22, 2026
概括
性瘤形态与肌肉侵入性膀癌 (MIBC) 的更高风险有关. 这种关联在小瘤 (≤3厘米) 和多个瘤 (>3) 的患者中更为强烈.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 膀癌 (BC) 诊断依赖于准确的分期来确定治疗.
- 肌肉侵入性膀癌 (MIBC) 需要积极的治疗策略.
研究的目的:
- 调查瘤形态与肌肉侵入性膀癌 (MIBC) 在新诊断的膀癌 (BC) 患者之间的关联.
主要方法:
- 对416名新诊断BC的患者进行了回顾性研究.
- 使用多变量逻辑回归评估了状形态和MIBC风险之间的关联.
- 控制年龄,性别,瘤大小,瘤数量和病理等级.
主要成果:
- 在MIBC患者中,性形态明显更为普遍 (68.8%对28.4%,p<0.001).
- 性瘤与三倍增加的MIBC风险有关 (OR = 3.1,p < 0.001).
- 这种关联对于≤3厘米 (OR = 3.9) 和>3个瘤 (OR = 5.1) 的瘤更为强烈.
结论:
- 在新诊断的BC患者中,性形态是MIBC的重要危险因素.
- 在小瘤 (≤3厘米) 和多个瘤 (>3) 的患者中,风险相关性被放大.
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