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Updated: Jan 23, 2026

De Novo Generation of Somatic Stem Cells by YAP/TAZ
13:05

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Published on: May 7, 2018

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巴斯罗巴里布通过稳定血管蛋白抑制YAP驱动的癌症

Young-Ju Kwon1,2, Dong Young Kim1, Yuna Kim1

  • 1Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.

Molecular oncology
|January 22, 2026
PubMed
概括

坦基拉酶抑制剂巴斯罗巴里布通过稳定血管蛋白 (AMOT) 来阻止YAP瘤基因来减少癌症生长. 这种药物克服了KRAS突变结直肠癌中MEK抑制剂的耐药性.

关键词:
对MEK抑制剂的耐药性产生阻力.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈血管新生素 (angiomotin) 是一种在巴斯罗巴里布 (basroparib) 的基础上.这是一种坦基拉酶抑制剂.

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