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Updated: Jan 24, 2026

Author Spotlight: A Computational Pipeline for Analyzing Chimeric Noncoding RNA-Target RNA Interactions in High-Throughput Sequencing Data
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Author Spotlight: A Computational Pipeline for Analyzing Chimeric Noncoding RNA-Target RNA Interactions in High-Throughput Sequencing Data

Published on: December 1, 2023

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长非编码RNA GAS5通过增加小密室RNA水平来破坏肠道上皮质屏障功能

Ting-Xi Yu1, Hee Kyoung Chung1, Amy VanderStoep1

  • 1Department of Surgery, University of Maryland School of Medicine, Baltimore, United States of America.

JCI insight
|January 22, 2026
PubMed
概括

长非编码RNA GAS5通过抑制粘膜生长和抑制紧密结合蛋白来破坏肠道屏障功能. 降低小鼠的GAS5水平改善了肠道屏障的完整性,为炎症性肠道疾病 (IBD) 提供了潜在的治疗点.

关键词:
细胞生物学 细胞生物学胃肠病学 胃肠病学紧密的结口是紧密的结口.

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