脂肪氧化中的性别差异取决于年龄,体重指数和运动方式:系统性审查和元分析
Carlo Ferri-Marini1, Octavia G Garcia Murillo2, Danna A Corral-Castillo2,3
1Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
International journal of sport nutrition and exercise metabolism
|January 22, 2026
概括
这项研究发现,虽然绝对最大脂肪氧化 (MFO) 在女性中较低,相对MFO和FATmax没有显著的性别差异. 运动强度和个人因素,如BMI和年龄,是运动期间脂肪代谢的关键调节者.
科学领域:
- 运动生理学 运动生理学
- 代谢健康 代谢健康
- 人类表现的人类表现.
背景情况:
- 运动代谢中的性二态性并未完全被理解.
- 最大脂肪氧化 (MFO) 和相关的运动强度 (FATmax) 是代谢灵活性的关键指标.
- 关于脂肪氧化中的性别差异的先前假设需要进行批判性评估.
研究的目的:
- 系统地审查和对MFO和FATmax的性二态现有证据进行元分析.
- 在不同人群中确定影响MFO和FATmax的关键调节者.
- 挑战现有的关于运动脂肪代谢性别差异的假设.
主要方法:
- 2001年1月至2024年4月期间发表的研究的系统审查和元分析.
- 包括36项研究 (n=8,990) 在分级运动测试中从间接热量计中报告性别特定的MFO和FATmax.
- 根据PRISMA 2020指南进行数据综合,在PROSPERO.中注册.
主要成果:
- 在女性中,绝对MFO显著较低 (-0.06g/min).
- 性别之间相对MFO或FATmax没有发现显著差异.
- 心血管健康,体重指数和运动模式 (与更高的MFO相关的跑步机) 是显著的调节者.
- 年龄与FATmax有曲线关系 (p = .008).
结论:
- 在运动期间女性脂肪氧化率较高的假设受到质疑.
- 脂肪代谢的性别差异取决于背景,需要个性化评估.
- 需要进一步的纵向研究来确定这些发现对心脏代谢的影响.
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