乳杆菌delbrueckii表面蛋白P4430通过调节巨细胞两极分化通过Mincle减轻肠道炎症

Xiangyu Zhang1, Xiangyi Zeng2, Yujun Wu2

  • 1State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China; Frontier Science Center of Molecular Design Breeding, Ministry of Education, Beijing 100193, China.

Cell reports
|January 22, 2026
PubMed
概括

乳酸菌delbrueckii,通常在性结肠炎 (UC) 中减少,其表面蛋白质P4430,可以减少肠道炎症. 通过准Mincle,P4430抑制了巨细胞的炎症反应,提供了潜在的UC疗法.

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