广泛的周周支柱下arachnoid出血: 脊柱arachnoid囊的发展的一个危险因素. 有关案例说明的例子
Laura Krismer1, Sameer Nazeeruddin1, Theo Demerath2
1Department of Neurosurgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Journal of neurosurgery. Case lessons
|January 22, 2026
概括
脊柱甲状腺囊 (SAC) 是神经瘤下甲状腺出血 (aSAH) 后的一种罕见并发症. 活跃的血液清理可以防止SACs,特别是在患有后部循环动脉瘤和大量出血的患者中.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
- 血管外科 血管外科
背景情况:
- 脊柱甲状腺囊 (SACs) 是罕见的,延迟的并发症后动脉瘤下甲状腺出血 (aSAH).
- 这些囊可能导致严重的脊髓损伤,病原体的理解不充分,预防策略有限.
- 在aSAH之后,SAC的管理仍然具有挑战性.
研究的目的:
- 调查aSAH患者中SACs的患病率.
- 确定与SAC发展相关的潜在风险因素和患者子组.
- 探索活跃血液清理在SAC预防中的潜在作用.
主要方法:
- 一个19年的aSAH患者机构登记册 (2005-2023) 的回顾性审查.
- 对1470名aSAH入院的分析,重点关注1098名六个月幸存者.
- 识别和描述患有症状,成像证实SACs的患者.
主要成果:
- 在1098名幸存者中,有5名患者 (0.46%) 发展出症状性SAC.
- 所有SAC病例都源于破裂的后部循环动脉瘤与广泛的周周干部出血 (在这个子组中占11.4%的患病率).
- 所有SAC患者都没有接受活跃的血液清理,这表明潜在的预防作用 (15.2%的患病率在这个群体). 骨髓病发作的中位时间为28个月.
结论:
- 脊柱甲状腺囊是aSAH的一个未被认可的并发症,主要发生在患有后部循环动脉瘤和广泛的周周结节出血的患者中.
- 在所有观察到的SAC病例中没有活跃的血液清理,这表明它具有作为预防措施的潜力.
- 对活跃的血液清理协议的进一步研究可能会减轻aSAH后SAC发展的风险.
相关概念视频
Factors Affecting the Risk of Infection
13.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.3K
Relative Risk
2.0K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.0K
Transcription Factors
82.3K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
82.3K
Factors Affecting Solubility
36.7K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Chȃtelier’s principle. Consider the dissolution of silver iodide:
36.7K
Transcription Elongation Factors
13.5K
Transcription elongation is a dynamic process that alters depending upon the sequence heterogeneity of the DNA being transcribed. Hence, it is not surprising that the elongation complex's composition also varies along the way while transcribing a gene.
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA...
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA...
13.5K
Factors Affecting Drug Distribution: Miscellaneous Factors
969
Drug distribution in the human body is a complex process influenced by various individual factors, including age, pregnancy, obesity, diet, body water composition, pH levels, and specific disease conditions.
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...
969


