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Updated: Jan 24, 2026

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
10:43

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Published on: December 23, 2022

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在口腔状细胞癌中,EP4刺激通过IL-6信号促进细胞粘附和迁移

Wakana Fukae1, Soichiro Ishikawa2, Yu Iida3

  • 1Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa 236-0004, Japan.

The journal of physiological sciences : JPS
|January 22, 2026
PubMed
概括

前列腺素E2 (PGE2) 受体EP4促进口腔状细胞癌 (OSCC) 细胞粘附和迁移. 这通过增加IN-6 (IL-6) 表达而发生,IN-6是OSCC进展的关键调解者.

关键词:
细胞粘附 细胞粘附细胞迁移 细胞迁移EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4 EP4介质蛋白-6 (IL-6) 介质蛋白-6 (IL-6) 是一种口腔状细胞癌 (OSCC) 是一种前列腺素E2 (PGE2) 是一种前列腺素.

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