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Updated: Jan 24, 2026

Crystal Structure of the N-terminal Domain of Ryanodine Receptor from Plutella xylostella
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Crystal Structure of the N-terminal Domain of Ryanodine Receptor from Plutella xylostella

Published on: November 30, 2018

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模拟使用GLP-1受体C端突变的G蛋白偏差激素

Hanh Duyen Tran1, Yiming Zuo1, Carissa Wong1

  • 1Section of Endocrinology, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Du Cane Road, W12 0NN, United Kingdom.

Molecular metabolism
|January 22, 2026
PubMed
概括

通过减少酸化来修改类似葡萄糖-1受体 (GLP-1R),可以增强G蛋白信号传递. 这种方法支持使用偏向激素来提高GLP-1R激素对2型糖尿病和肥胖症治疗的疗效.

关键词:
在GLP-1受体.有偏见的激进主义.这是一种β-arrestin.

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