在蛇中,肺周围循环的管控制调节了温度变化相关的血液动力学调整
Samanta A Castro1, Edwin W Taylor2, Renato Filogonio3
1Department of Physiological Sciences, Federal University of São Carlos (UFSCar), São Carlos, SP, Brazil.
概括
蛇调整血液氧化,而不是血液流动,以满足不断变化的代谢需求. 肺动脉的神经调节对于这种适应至关重要,即使一个迷走神经被切除.
科学领域:
- 比较生理学比较生理学
- 心血管生理学心血管生理学
- 类学 类学 类学 类学
背景情况:
- 对肺动脉的阴道影响已知在 Squamates.
- 肺循环往往对调节器的反应不如系统循环.
- 在以前的研究中,麻醉可能掩盖了肺电路反应.
研究的目的:
- 在蛇中研究肺循环的阴道调节.
- 确定蛇如何适应不同体温的新陈代谢需求的变化.
- 探索迷走神经在调节肺血管音调中的作用.
主要方法:
- 使用了无脑蛇模型.
- 与左侧静脉瘤 (LV) 和非静脉瘤 (NV) 的蛇进行比较.
- 在10,20和30°C的体温下测量心血管和呼吸系统参数.
主要成果:
- 有氧代谢随着体温的增加而增加.
- 系统导电性保持稳定;右向左的分流减少.
- 左静止蛇通过调节肺导电性来维持氧气吸收来弥补减少的肺顺应.
结论:
- 蛇改变血液的氧化,而不是 perfusion,以满足有氧需求.
- 周围肺循环是血管对温度变化的调整的关键.
- 在蛇的肺部中存在双边阴道内,左侧和右侧阴道有不同的作用.
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