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Updated: Jan 24, 2026

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
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分子和染色体可访问性计划是新生儿死性肠球炎的表皮损伤和受损再生的基础

Yi Xiong1, Andrea Zito2, Haoyan Liang3

  • 1Department of General Surgery, Capital Institute of Pediatrics Affiliated Children's Hospital, Beijing,100020, China; Translational Medicine, The Hospital for Sick Children, 686 Bay Street, Toronto, Ontario, M5G0A4, Canada.

Cellular and molecular gastroenterology and hepatology
|January 22, 2026
PubMed
概括

新生儿死性肠球炎 (NEC) 通过破坏干细胞功能,损害肠道修复. 这项研究确定Ezh2是肠干细胞 (ISC) 的关键调节者,并建议准Ezh2和WNT信号,以恢复NEC的肠道完整性.

关键词:
死性肠球炎 (NEC) 是一个疾病.一个单细胞分析.这就是表观遗传学.肠道上皮细胞 肠道上皮细胞肠道有机体是什么意思肠道干细胞是什么?肠道干细胞是什么?转录规则 转录规则 转录规则

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