大--阿加兰混合物作为天然抗氧化剂候选人用于营养药物应用
Maylla Maria Correia Leite Silva1, Ariana Pereira da Silva2, João Pedro Bauman Quieregati1
1Postgraduate Program in Biochemistry and Molecular Biology, Center for Biosciences, Federal University of Rio Grande do Norte (UFRN), Natal, RN, 59078-970, Brazil; Natural Polymer Biotechnology Laboratory (BIOPOL), Department of Biochemistry, Center of Biosciences, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, 59078-970, Brazil.
International journal of biological macromolecules
|January 22, 2026
概括
将大和提取物与海洋混合,显示出增强的抗氧化特性和稳定性. 这种生物相容混合物为营养药和制药应用提供了更安全的替代方案,减少了潜在的不良影响.
科学领域:
- 海洋生物技术 海洋生物技术
- 食品科学 食品科学 食品科学
- 生物化学 生物化学
背景情况:
- 氧化应激与慢性疾病有关,需要有效的抗氧化剂解决方案.
- 大 (Allium sativum) 和 (Citrus limon) 提供生物活性化合物,但面临生物可用性和不良影响限制.
- 像阿加兰这样的海洋多糖类具有作为增强抗氧化特性矩阵的潜力.
研究的目的:
- 开发和描述和提取物 (LG) 和来自Gracilaria birdiae (SPGB) 的硫化的混合配方.
- 为了评估这些混合物的氧化还原行为,抗氧化特性和生物相容性.
- 探索LG:SPGB混合物的潜力,作为营养药和制药用途的抗氧化系统.
主要方法:
- 混合配方的制备,将水性大和提取物 (LG) 与硫酸 (SPGB) 结合起来.
- 在体外测试以评估氧化还原行为和抗氧化性质 (降解能力,金属化).
- 细胞毒性测试和Danio rerio胚胎毒性测定用于生物相容性评估.
主要成果:
- 与LG单独相比,LG:SPGB (3:1) 混合物表现出优越的降解能力和金属化活性.
- 混合物表现出更好的稳定性和减少细胞毒性作用.
- 阿加兰促进了抗氧化物质的维护,具有较低度的-提取物,减轻了不良影响.
结论:
- 大--阿加兰混合物是有前途的生物相容抗氧化剂系统.
- 加入海洋多糖化合物增强了植物提取物的稳定性和安全性.
- 这些混合物有可能在营养药和制药行业应用.
关键词:
功能性配方是指功能性的配方.这种植物是Gracilaria birdiae.在体外抗氧化剂试验中进行抗氧化剂测定.氧化应激是一种氧化应激.硫酸多糖化合物 硫酸多糖化合物斑马鱼胚胎毒性 斑马鱼胚胎毒性更多相关视频
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