来自胰腺的外宫上皮上腺癌:一个病例报告与文献综述
Alperen Onur İşler1,2, Nezih Akkapulu3, Altan Kavuncuoğlu4
1Division of Endocrinology and Metabolism, Hacettepe University School of Medicine, Ankara, Turkey.
International journal of surgical pathology
|January 22, 2026
概括
宫外上皮癌 (ACC) 是罕见的,这一病例详细说明了第一个起源于胰腺的ACC病例. 这一发现强调了在非上腺瘤中考虑ACC的重要性.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 上腺残留的恶性瘤是非常罕见的,由于胚胎发育,可以在子宫外发生.
- 宫外上皮癌 (ACC) 是一种罕见的实体,在各种非上腺部位有记录的发生.
研究的目的:
- 报告第一个诊断的宫外 adrenocortical 癌症 (ACC) 发生在胰腺的病例.
- 审查外阴ACC的文献,并强调在非上腺瘤的差异诊断中考虑其.
主要方法:
- 一个57岁的女性患者的案例研究,诊断出异位胰腺ACC.
- 诊断评估包括成像和病理检查与免疫组织化学染色 (SF-1).
- 胰腺质量的外科切除,然后进行辅助疗法 (米托坦和葡萄糖皮质激素替代).
主要成果:
- 鉴定出位于胰腺的左侧前大动脉区域的一个6厘米,周边形状良好,异质的质量.
- 病理学检查证实了一种细胞类型的ACC,具有高核级和SF-1阳性.
- 患者没有表现出荷尔蒙功能过高的迹象,目前没有复发或转移.
结论:
- 这是第一个报告的异位上皮癌 (ACC) 病例,起源于胰腺.
- 宫外ACC应该包括在非上腺部位发现的瘤的差异诊断中.
- 早期诊断和适当的治疗对于异位ACC患者至关重要.
相关概念视频
Cancers Originate from Somatic Mutations in a Single Cell
14.7K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
14.7K
Pancreas
2.2K
The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...
2.2K
Review and Preview
8.3K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.3K
Review and Preview
10.9K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
10.9K
Cells and Secretions of the Pancreas
4.6K
The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
4.6K
Data Reporting and Recording
5.4K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K


