优化最初的冲压压力在异常性正常压力水脑的优化
Rodolfo Casimiro Casimiro Reis1, Miguel Bertelli Ramos1, Igor Napoleão Paiva Araújo1
1Neurosurgery, Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brazil.
概括
设置 idiopathic normal pressure hydrocephalus (iNPH) 的初始开口压力为 6.5 厘米 H2O,为 3 厘米 H2O 提供类似的临床改善,但减少过度排水并发症.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
- 医疗器械 医疗器械
背景情况:
- 异常正常压力头症 (iNPH) 的管理通常使用可编程门的初始开放压力较低.
- 对于iNPH变速器,最优的初始低压设置尚未得到确立.
- 这项研究调查了不同初始打开压力的有效性和安全性.
研究的目的:
- 为了确定iNPH患者可编程门的最佳初始打开压力.
- 为了比较3厘米H2O和6.5厘米H2O初始开口压力之间的临床疗效和并发症率.
主要方法:
- 在分流手术后,iNPH患者的潜在随访.
- 使用可编程,其初始开口压力为3厘米H2O或6.5厘米H2O.
- 在一年内评估临床改善和并发症.
主要成果:
- 在3厘米H2O和6.5厘米H2O组之间,临床改善 (iNPH日本尺度) 没有显著差异.
- 与6.5厘米H2O组 (0%) 相比,在3厘米H2O组 (10.5%) 中需要手术的皮肤下排泄的发生率更高.
- 对于皮下排泄的统计学意义:p=0.043.
结论:
- 在可编程门中,6.5厘米H2O的初始打开压力为iNPH提供了与3厘米H2O相比的临床结果.
- 较高的初始开口压力 (6.5厘米H2O) 与较少的过度排水并发症有关.
- 6.5厘米的H2O可能是一个更安全的初始设置,用于iNPH变速管理.
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