RIG-I激动剂促进抗原扩散,并促进胰腺管道腺癌中持久的CAR-T反应

Anne Marie Senz1, Bruno L Cadilha2, Julia Teppert1

  • 1Institute of Clinical Pharmacology, LMU University Hospital, LMU Munich, Munich, Germany.

概括

合成的3p-RNA (酸诱导基因I激动剂) 与CAR-T疗法相结合,通过重编程瘤微环境和增强T细胞反应,有效治疗胰腺癌,从而产生持久的免疫力.

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