外科手术的持续时间作为一个预测器的静脉血栓栓塞风险后的激进囊切除术
Furkan Dursun1, Burak Akgul2, Jonathan A Gelfond3
1Department of Urology, University of Texas Health Science Center at San Antonio, San Antonio, TX; University of Texas Health Science Center at San Antonio/MD Anderson Mays Cancer Center, San Antonio, TX.
Urologic oncology
|January 22, 2026
概括
较长时间的激进囊切除术 (RC) 增加了静脉血栓塞栓症 (VTE) 的风险. 超过6小时的每小时都会使VTE风险增加16%,这凸显了优化手术持续时间的必要性.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术瘤学手术瘤学
- 血管外科 血管外科
背景情况:
- 激进囊切除术 (RC) 是用于膀癌的重大手术.
- 静脉血栓塞栓症 (VTE) 是RC后的一个重要并发症.
- 运行时间 (OD) 是VTE的潜在可修改的风险因素.
研究的目的:
- 评估RC患者的手术持续时间 (OD) 和症状性VTE之间的关联.
- 确定增加VTE风险的OD值.
- 量化与长期OD相关的额外VTE风险.
主要方法:
- 分析国家外科质量改善计划数据库 (2007-2022年).
- 包括24503名接受激进囊切除术的患者.
- 多变量后勤回归以确定VTE的独立预测因子,控制混因子.
主要成果:
- 在手术后30天内,VTE发生在3.6%的患者中.
- 超过6小时的操作持续时间是静脉瘤的独立预测因子 (OR 1.16).
- 超过6个小时的每一个额外小时,VTE风险增加了16%.
结论:
- 在急性囊切除术中,延长的手术持续时间显著增加了静脉瘤风险.
- 确定了6小时的操作持续时间值,超过这个值后,风险会升级.
- 优化手术效率和减少手术持续时间的策略可以减轻RC患者的静脉瘤并发症.
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