与植入物相比,两片的临床和放射性结果的一年分析:多中心前性随机临床试验
Marc Balmer1, Michael Payer2, Anke Steinwender3
1Clinic of Reconstructive Dentistry, Center for Dental Medicine Zurich, University of Zurich, Zurich, Switzerland.
Clinical oral implants research
|January 22, 2026
概括
这项研究发现,在使用一年后,和植入物之间没有显著的临床差异. 两种植入物类型都显示出相似的边际骨损失,存活率和植入周围健康状况,这表明石是一种可行的替代品.
科学领域:
- 牙科植入物学 牙科植入物学
- 生物材料科学 生物材料科学
背景情况:
- 无金属牙植入物的开发是由患者对美学和生物相容解决方案的需求驱动的.
- 晶植入物为传统的植入物提供了牙颜色的替代品.
- 评估石植入物的长期临床性能对于其广泛采用至关重要.
研究的目的:
- 为了比较两片嵌体与嵌体的临床性能.
- 为了评估边际骨损失 (MBL),存活率,并在装载一年后围植软组织的健康状况.
主要方法:
- 一个多中心,前性,随机的临床试验,涉及122名患者 (61名,61名植入物).
- 植入物用单个皇冠恢复,并在安置,皇冠交付和1年后装载时进行评估.
- 关键的结果措施包括MBL,生存率,早期伤口愈合和软组织参数.
主要成果:
- 在 (0.94 ± 0.67毫米) 和 (1.10 ± 0.78毫米) 植入物之间没有观察到统计学上显著的MBL差异.
- 植入物在一年后实现了100%的存活率,而植入物在一年后的存活率为96.5%.
- 周围植入物软组织参数,包括探测深度和斑块积累,在两组之间是可比的.
结论:
- 一年后,和植入物在MBL和周围植入物健康方面表现相似的临床性能.
- 植入物的生存率与植入物相比并非劣.
- 两块石植入物代表了单一牙修复的临床可行的替代方案.
相关概念视频
Clinical Trials
10.2K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
10.2K
Clinical Trials: Overview
4.7K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.7K
Statistical Software for Data Analysis and Clinical Trials
1.4K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.4K
Nursing Clinical Information System
1.3K
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.3K
Changes in Skin Color: Clinical Perspectives
3.4K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.4K
COPD: Pathogenesis and Clinical Features
1.8K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.8K


