相关实验视频
Updated: Jan 24, 2026

10:02
Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
15.2K
当代系列的小儿科患者的跨形微手术
Stefanie Ott1, Nora Ramdani2, Lasse Dührsen1
1Department of Neurosurgery, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Neurosurgical review
|January 22, 2026
概括
儿科垂体瘤是多样化的,小孩常见的瘤和年长儿童的垂体腺瘤/PitNETs. 手术的持续时间与年龄和状鼻发育相关.
科学领域:
- 儿科神经外科 儿科神经外科
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
背景情况:
- 下垂体瘤在儿童中很少见,占儿童瘤的不到10%.
- 膜瘤是最常见的儿科细胞损伤,而垂体腺瘤/PitNETs占细胞损伤的2-8%.
研究的目的:
- 为了分析十年的小儿小术患者的跨形微手术结果.
- 检查儿科垂体病变中的外科手术期间的特征,并发症,临床结果和解剖特征.
主要方法:
- 从2013年到2023年对122名儿科患者 (年龄在18岁以下) 进行的147次跨形手术的回顾性分析.
- 评估年龄,性别,激素产生,组织病理学,放射学,手术数据,并发症和复发率.
主要成果:
- 头骨瘤是最常见的 (34.4%),特别是在10岁以下的儿童中 (58.6%).
- 垂体腺瘤/PitNETs (31.1%) 在年龄较大的儿童中更为普遍;皮质和乳质腺瘤是最常见的亚型.
- 手术持续时间随着年龄的增长而减少,与状鼻肺炎相反相关.
结论:
- 儿科垂体损伤人口统计显示了年龄依赖的模式:头骨瘤在较小的儿童中占主导地位,而垂体腺瘤/PitNET在10岁后的患病率增加.
- 儿科患者的跨形手术需要考虑与年龄相关的解剖学差异和病变类型.
相关概念视频
Pharmacokinetics in Pediatric Patients: Drug Excretion
214
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
214
Pharmacokinetics in Pediatric Patients: Drug Distribution
271
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
271
Pharmacokinetics in Pediatric Patients: Drug Metabolism
199
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
199
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
260
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
260
Contemporary Psychology
2.2K
Psychology explores human behavior and mental processes through various lenses, each offering unique insights. This overview examines key subfields, including biopsychology, evolutionary, developmental, personality, and social psychology, highlighting their approaches and contributions to understanding complex human behaviors.
Biopsychology
Biopsychology, also known as biological psychology or behavioral neuroscience, focuses on the biological underpinnings of behavior and mental processes. It...
Biopsychology
Biopsychology, also known as biological psychology or behavioral neuroscience, focuses on the biological underpinnings of behavior and mental processes. It...
2.2K
Resistors In Series
6.1K
A resistor is an ohmic device that limits the flow of charge in a circuit. Most circuits have more than one resistor. If several resistors are connected together and connected to a battery, the current supplied by the battery depends on the equivalent resistance of the circuit. The equivalent resistance of a combination of resistors depends on both their individual values and how they are connected. The simplest combination of resistors is the series combination.
In a series circuit, the...
In a series circuit, the...
6.1K

